A 54-year-old woman is involved in an automobile accident and requires a blood transfusion. Five hours later, she becomes febrile and has severe back pain. Laboratory studies show evidence of intravascular hemolysis. It is discovered that type A Rh+ blood was given by mistake to this type B Rh+ patient. Which of the following best explains the development of intravascular hemolysis in this patient?
A 54-year-old woman is involved in an automobile accident and requires a blood transfusion. Five hours later, she becomes febrile and has severe back pain. Laboratory studies show evidence of intravascular hemolysis. It is discovered that type A Rh+ blood was given by mistake to this type B Rh+ patient. Which of the following best explains the development of intravascular hemolysis in this patient?
💡 Explanation
A 54-year-old woman is involved in an automobile accident and requires a blood transfusion. Five hours later, she becomes febrile and has severe back pain. Laboratory studies show evidence of intravascular hemolysis. It is discovered that type A Rh+ blood was given by mistake to this type B Rh+ patient. Which of the following best explains the development of intravascular hemolysis in this patient?
✓ Correct Answer: B. Antibody-mediated complement fixation
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