Medical MCQ - A 50-year-old man Shahid K. John has had increasing dyspnea for the past 3 years with associated occasional cough but little sputum production. Auscultation reveals that his lungs are hyper-resonant and is associated with expiratory wheeze. Pulmonary function tests reveal increased total lung capacity (TLC) and slightly increased FVC. There is decreased FEV1 and FEV1/FVC ratio also. ABG analysis reveals pH of 7.35, pO2 of 60 mm Hg and pCO2 of 48 mm Hg. What is the most likely diagnosis?

A 50-year-old man Shahid K. John has had increasing dyspnea for the past 3 years with associated occasional cough but little sputum production. Auscultation reveals that his lungs are hyper-resonant and is associated with expiratory wheeze. Pulmonary function tests reveal increased total lung capacity (TLC) and slightly increased FVC. There is decreased FEV1 and FEV1/FVC ratio also. ABG analysis reveals pH of 7.35, pO2 of 60 mm Hg and pCO2 of 48 mm Hg. What is the most likely diagnosis?

Centriacinar emphysema

Sarcoidosis

Diffuse alveolar damage

Chronic pulmonary embolism

Question Category:

Pathology

Correct Answer:

Centriacinar emphysema

Description:

The findings of Mr. John point to an obstructive lung disease like emphysema which occurs due to airway narrowing or even from loss of elastic recoil. So, emphysema is the most likely diagnosis. • Sarcoidosis is a chronic restrictive lung disease with all lung volumes decreased, low FVC, and normal FEV1/FVC ratio. • Diffuse alveolar damage is an acute restrictive lung disease. • Chronic pulmonary embolism does not affect FVC because the airways are not affected. It is however associated with a ventilation/perfusion mismatch.

Previous MCQ

Next MCQ

Get More

Subject Mock Tests

Try practicing mock tests with over 200,000 questions from various medical subjects.

Attempt a mock test now

Mock Exam

Attempt an exam of 100 questions randomly chosen from all subjects.

Coming Soon