A 5-year old child of severe nephrotic syndrome on treatment with tacrolimus, frusemide and prednisolone developed seizures. The investigations revealed:
Serum Na+ = 136 mEq/L
Blood urea = 78 mg/dL
Serum creatinine = 0.5 mg/dL
Serum albumin = 1.5 g/dL
Serum total Ca = 7.5 mg/dL
Urine albumin = 2g
What is the likely cause of symptoms in this baby?
A 5-year old child of severe nephrotic syndrome on treatment with tacrolimus, frusemide and prednisolone developed seizures. The investigations revealed:
Serum Na+ = 136 mEq/L
Blood urea = 78 mg/dL
Serum creatinine = 0.5 mg/dL
Serum albumin = 1.5 g/dL
Serum total Ca = 7.5 mg/dL
Urine albumin = 2g
What is the likely cause of symptoms in this baby?
π‘ Explanation
A 5-year old child of severe nephrotic syndrome on treatment with tacrolimus, frusemide and prednisolone developed seizures. The investigations revealed:
Serum Na+ = 136 mEq/L
Blood urea = 78 mg/dL
Serum creatinine = 0.5 mg/dL
Serum albumin = 1.5 g/dL
Serum total Ca = 7.5 mg/dL
Urine albumin = 2g
What is the likely cause of symptoms in this baby?
β Correct Answer: B. Tacrolimus toxicity
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