A 44-year-old businessman presents to a physician because of a markedly inflammed and painful right great toe. He states that he just returned from a convention, and had noticed increasing pain in his right foot during his flight back home. Physical examination is remarkable for swelling and erythema of the right great toe as well as small nodules on the patient’s external ear. Aspiration of the metatarsal-phalangeal joint of the affected toe demonstrates needle-shaped negatively birefringent crystals. Which of the following agents would provide the most immediate relief for this patient?
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