Medical MCQ-A 43 year old female presented with pigmentation on neck, axilla and other flexures. She is diabetic for few years and not under control. She is worried about the chance of skin cancer. All of the following are premalignant conditions, EXCEPT:

A 43 year old female presented with pigmentation on neck, axilla and other flexures. She is diabetic for few years and not under control. She is worried about the chance of skin cancer. All of the following are premalignant conditions, EXCEPT:

Solar keratosis

Acanthosis nigricans

Bowen's disease

Porokeratosis

Question Category:

Skin

Correct Answer:

Acanthosis nigricans

Description:

Acanthosis nigricans is probably the most readily recognized skin manifestation of diabetes and most cases are linked to obesity and insulin resistance. True association is rare between acanthosis nigricans and malignancy. It presents as brown to gray-black papillomatous cutaneous thickening in the flexural areas, including the posterolateral neck, axillae, groin, and abdominal folds. Ref: Kalus A.A., Chien A.J., Olerud J.E. (2012). Chapter 151. Diabetes Mellitus and Other Endocrine Diseases. In L.A. Goldsmith, S.I. Katz, B.A. Gilchrest, A.S. Paller, D.J. Leffell, N.A. Dallas (Eds), Fitzpatrick's Dermatology in General Medicine, 8e.

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