A 40 years old patient with liver dysfunction is scheduled for a surgical procedure. Lorazepam can be used for pre-anaesthetic medication in this patient without concern for excessive CNS depression because the drug is:
Correct Answer: Conjugated directly
Description: (Ref: Katzung 6/e p450) Lorazepam and oxazepam are the benzodiazepines which are excreted from the body by glucuronide conjugation without phase 1 metabolism in the liver. So these can be used safely in hepatic dysfunction.
Category:
Anatomy
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now