A 40 years old female was admitted to our hospital with a history of severe pain in the left forearm and left ankle following tril injury. She had difficulty in walking and a swelling in right upper leg. She had pain in the ankle along with painful movements of the ankle joint for about two years. Relevant abnormal biochemical parameters were -raised serum calcium (11.9 mg/dl ), raised alkaline phosphatase (717 U/L), low inorganic phosphorus (1.3 mg/dl) and raised serum parathyroid hormone (1265 pg/l). Protein electrophoresis for M band was negative. X-ray of right leg is given below. What is the most common site of lesion shown above?

Correct Answer: Mandible
Description: The radiological features of browns tumors in the repoed cases mainly consisted of single or multiple well-defined osteolytic lesions, single or multi-lobular, usually with bone expansion and can demonstrate bony destruction and be associated with pathological fractures. Brown tumors may be located in any pa of the skeleton. Involvement of the mandible, maxilla, palate, nasal cavity, paranasal sinuses, and orbital and temporal bones has been repoed. The mandible is more commonly affected than the maxilla, and these tumors are usually asymptomatic except when large.
Category: Radiology
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