A 40-year-old developed pathological fractures and was found to be having low bone density after a Dexa Scan. Laboratory tests show low plasma calcium, elevated PTH levels, and low vitamin D levels. The patient is on a balanced diet. However, the patient’s plasma creatinine and urea are elevated markedly. Which of the following is the most likely reason for the hypocalcemia and reduced bone mass?
A 40-year-old developed pathological fractures and was found to be having low bone density after a Dexa Scan. Laboratory tests show low plasma calcium, elevated PTH levels, and low vitamin D levels. The patient is on a balanced diet. However, the patient’s plasma creatinine and urea are elevated markedly. Which of the following is the most likely reason for the hypocalcemia and reduced bone mass?
💡 Explanation
A 40-year-old developed pathological fractures and was found to be having low bone density after a Dexa Scan. Laboratory tests show low plasma calcium, elevated PTH levels, and low vitamin D levels. The patient is on a balanced diet. However, the patient's plasma creatinine and urea are elevated markedly. Which of the following is the most likely reason for the hypocalcemia and reduced bone mass?
✓ Correct Answer: D. Reduced renal activity of 1 alpha-hydroxylase activity
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