A 38-year-old woman presents to the clinic with new symptoms of palpitations, weight loss, and heat intolerance. On physical examination, she has a mild tremor of her outstretched hands, an enlarged thyroid, and resting tachycardia (heart rate 110/min). Biochemical tests confirm the diagnosis and she is started on methimazole. Which of the following is the most likely mechanism of this drug?
A 38-year-old woman presents to the clinic with new symptoms of palpitations, weight loss, and heat intolerance. On physical examination, she has a mild tremor of her outstretched hands, an enlarged thyroid, and resting tachycardia (heart rate 110/min). Biochemical tests confirm the diagnosis and she is started on methimazole. Which of the following is the most likely mechanism of this drug?
💡 Explanation
A 38-year-old woman presents to the clinic with new symptoms of palpitations, weight loss, and heat intolerance. On physical examination, she has a mild tremor of her outstretched hands, an enlarged thyroid, and resting tachycardia (heart rate 110/min). Biochemical tests confirm the diagnosis and she is started on methimazole. Which of the following is the most likely mechanism of this drug?
✓ Correct Answer: B. inhibition of thyroidal organic binding and coupling reactions
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