A 35 year old obese female with deteriorating hirsutism and high testosterone. True is
Correct Answer: She is at risk of endometrial cancer
Description: Consequences of Polycystic Ovarian SyndromeSho-Term ConsequencesLong-Term ConsequencesMenstrual dysfunction (Irregular menses)AmenorrheaOligomenorrheaEpisodic menometrorrhagiaHyperandrogenismHirsutismAcneAndrogenic alopeciaInfeilityObesityInsulin resistance (Acanthosis nigricans)Dyslipidemia (Androgenic lipoprotein profile)|LDL|TG|Total cholesterol: HDL ratio|HDLMetabolic syndrome - Characterized by insulin resistance, obesity, androgenic dyslipidemia and hypeensionObstructive sleep apnea (Related to central obesity and dyslipidemia)Diabetes mellitus Increased risk of impaired glucose tolerance and type 2 DM in PCOS patientsCardiovascular diseases: Greater prevalence of atherosclerosis and cardiovascular disease with an increased risk of myocardial infarctionCancerEndometrial carcinoma (3 fold increase risk)Ovarian cancerWomen with PCOS are associated with a definite increased risk of endometrial cancer. An increased risk of ovarian cancer and breast cancer has also been suggested.(Refer: Novak&;s Textbook of Gynaecology, 14th edition, pg no-1077)
Category:
Pathology
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