A 30 year old man who was recently started on haloperidol 30mg/day developed hyperpyrexia, muscle rigidity, akinesia, mutism, sweating, tachycardia and increased blood pressure. The investigations showed increased WBC count, increased creatinine phosphokinase. There is no history of any other drug intake or any signs of infection. The most likely diagnosis –
Correct Answer: Neuroleptic malignant syndrome
Description: Features of neuroleptic malignant syndrome
Marked muscular rigidity
High fever
Autonomic instability (↑ HR & BP, Sweating)
Disturbed consciousness
Catatonia & stupor
Leucocytosis
Increased CPK
Myoglobinemia & Myoglobinuria
Category:
Psychiatry
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