Medical MCQ-A 30 year old male patient was on Isoniazid therapy for Tuberculosis.He developed rashes on exposed pas of body.He has disoriented memory. Family members gives history of diarrhea also.What is the diagnosis?

A 30 year old male patient was on Isoniazid therapy for Tuberculosis.He developed rashes on exposed pas of body.He has disoriented memory. Family members gives history of diarrhea also.What is the diagnosis?

Isoniazid neuropathy

Tuberculosis skin lesions

Niacin deficiency

Some other drugs has caused this

Question Category:

Biochemistry

Correct Answer:

Niacin deficiency

Description:

Isoniazid inhibits the endogenous syntheisis of Niacin so,the patient developed dermatitis,diarrhea,dementia. Prolonged treatment with Isoniazid leads to Pyridoxine deficiency,which is required for endogenous synthesis of niacin Reference: Harpers illustrated biochemistry 30th edition

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