A 3-year-old child presented with fatigue, malaise, fever, sore throat, headache, nausea, abdominal pain and myalgia. O/E Generalized lymphadenopathy Hepatosplenomegaly, Tonsillar enlargement Palatal petechiae Rashes and edema of the eyelids. Some weird cells were observed in the peripheral blood. A specific serological test was performed Which of the following receptor is involved in the pathogenesis of the above disease: –
Correct Answer: CD21
Description: This is a case of Infectious mononucleosis. So, there are no B-cells in X-linked agammaglobulinemia to be affected. 1st image shows tonsillitis with membrane formation Peripheral blood film shows atypical lymphocytes or Downey cells are lymphocytes that become large as a result of antigen stimulation. B cells are the main reservoir of infection. An EBV envelope glycoprotein binds CD21 (CR2), the receptor for the C3d component of complement, which is present on B cells.
Category:
Unknown
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now