Medical MCQ-A 3–month old male child with normal genitalia presents to the emergency department with severe dehydration, hyperkalemia and hyponatremia. The measurement blood levels of which of the following will be helpful?

A 3–month old male child with normal genitalia presents to the emergency department with severe dehydration, hyperkalemia and hyponatremia. The measurement blood levels of which of the following will be helpful?

17–hydroxy progesterone

Renin

Cortisol

Aldosterone

Question Category:

Pediatrics

Correct Answer:

17–hydroxy progesterone

Description:

This is a case of congenital adrenal hyperplasia due to deficiency of 21 - hydroxylase deficiency. Because of the enzyme block ,there is increased formation of 17- hydroxyprogesterone, which is then shunted into the production of testosterone. Levels of cortisol and aldosterone are reduced.

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