A 28-year-old woman presents with a recent episode of coughing up some blood, frequent nosebleeds, and now decreased urine output. A nasal mucosa ulcer was seen on inspection. Her urinalysis is positive for protein and red cells consistent with a GN. The CXR shows two cavitary lesions and her serology is positive for antineutrophil cytoplasmic antibodies (ANCA). Which of the following is the most likely diagnosis?
Correct Answer: Wegener's granulomatosis
Description: Numerous diseases are associated with renal and pulmonary manifestations, including lupus, Goodpasture's syndrome, and Wegener's granulomatosis. Wegener's is typically associated with antineutrophil cytoplasmic antibodies.
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