A 25-year-old woman presents with a 2-week history of febrile illness and chest pain. She has an erythematous, macular facial rash and tender joints, paicularly in her left wrist and elbow. A CBC shows mild anemia and thrombocytopenia. Coicosteroids are prescribed for the patient. This medication induces the synthesis of an inhibitor of which of the following enzymes in inflammatory cells?
Correct Answer: Phospholipase A2
Description: Coicosteroids Used to suppress the tissue destruction associated with many chronic inflammatory diseases, including RA and systemic lupus erythematosus. Induce the synthesis of an inhibitor of phospholipase A2 and block the release of arachidonic acid from the plasma membranes of inflammatory cells. Myeloperoxidase catalyzes the conversion of H2O2 , in the presence of a halide (e.g., chloride ion) to form hypochlorous acid. Superoxide dismutase reduces the superoxide radical to H2O2.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now