A 25 year – old female gives a history of redness, pain and mild diminution of vision in one eye for past 3 days . There is also a history of low backache for the past one year. On examination there is circumcorneal congestion, cornea is clear apa from a few fine keratic precipitates on the corneal endothelium, there are 2+ cells in the anterior chamber, anterior chamber depth being normal and the intraocular pressure is within normal limits. The patient is most likely suffering from :
Correct Answer: HLA B-27 related anterior uveitis
Description: History of backache with features of anterior uveitis(circumcorneal congestion, few fine keratic precipitates on the corneal endothelium, 2+ cells in the anterior chamber )point towards HLA B27 associated uveitis. Seronegative spondyloahropathies-all are HLA B-27 positive . Sacrolitis (low back pain ) is earliest manifestation. M/C Extra Aicular Manifestation- Uveitis JIA(Juvenile Idiopathic Ahritis)- It usually develops before the age of 6 years. Pauciaicular, ANA positive , RF negative In 75% of Patients suffering from JIA associated with anterior uveitis have antinuclear antibodies (ANA) positive (HIGHEST association) In 50% of Patients suffering from JIA associated with anterior uveitis have predisposition due to HLA-DW5
Category:
Ophthalmology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now