A 24-year-old comes with a chief complaint of hair growth all over body. She repos that her menses began at the age of 13 years and has always been very irregular. She also complains of acne. On physical examination there is hair around the nipples, chin and upper lip. There is no galactorrhea, thyromegaly, or temporal balding on examination. Pelvic examination is normal, and there is not evidence of clitoromegaly. All of the following should be included in the differential diagnosis based on the patient’s history and physical examination, except :
Correct Answer: Seoli-Leydig cell tumor
Description: Seoli-Leydig cell tumors Occurs commonly in third or fouh decade of life These tumours are rare and account for 2% of all ovarian neoplasms They secrete androgens and cause defeminisation followed by masculinisation The women experiences oligomenorrhea followed by amenorrhea, flattening of breasts, acne, hirsutism, enlargement of clitoris and finally change in voice SHAW'S TEXTBOOK OF GYNECCOLOGY, 15th edition; Pg no:425
Category:
Gynaecology & Obstetrics
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