A 22yrs female was admitted in emergency with c/o nausea, vomiting, and watery diarrhoea since 4 days. He is also having low grade fever. He was hospitalised and treated symptomatically and was being relieved and discharged. His blood samples were sent for culture; repos of which pt. brought during his follow up – which showed the presence of clostridium perfringens. Being his physician what should be your next instruction to such patient –
Correct Answer: Return for IV penicillin therapy.
Description: Clostridia Spore bearing, obligate anaerobes and gram positive organisms. Reside normally in GI tract; although they have the propensity to cause fulminant bacteremia, but it is rare. In this question, pt. is well after an acute episode of illness; rules out fulminant course. So, a transient self-limited bacteraemia due to transient gut translocation could occur mostly during an episode of gastroenteritis and doesn't require treatment and fuher workup. So, among the given options returning for penicillin therapy is the best answer.
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