A 20-day old neonate presented with history of non-passage of meconium along with rectal prolapse, poor growth and delayed maturation. She has been hospitalized for the past 10 days due to respiratory tract infection. O/E Increased anteroposterior diameter of the chest Generalized hyperresonance Scattered coarse crackles Digital clubbing Protuberant abdomen Decreased muscle mass X ray abdomen was done. X ray abdomen was done. USG Abdomen ( Seen in antenatal records) All of the following drugs can be used in the treatment of the above-mentioned disease except: – Ivacaftor Dornase alpha Pulmozyme Mannitol