The patient is having symptoms of hypothyroidism and thryoid profile reveals primary hypothyroidism. Analyzing all options, Graves' disease and McCune-Albright syndrome are associated with hypehyroidism. (excludes 'a' & 'b') In pituitary adenoma/TSH-secreting pituitary tumor - increased TSH with increased T3/T4 would be seen. (option 'c' excluded) Primary hypothyroidism is d/t defect in thyroid gland itself; associated with high TSH & low free T4 levels. Hashimoto's thyroiditis is a cause of primary hypothroidism.