A 15-year-old boy is injured while playing cricket. X-rays of the leg rule out of a possible fracture. The radiologist repos the boy has an evidence of aggressive bone tumor with both bone destruction and soft tissue mass. The bone biopsy reveals a bone cancer with neural differentiation. Which of the following is the most likely diagnosis?

Correct Answer: Ewing's sarcoma
Description: synol sarcoma : Clinical presentation Symptoms * Local pain- universal complaint- intermittent, mild at first increase in severity with time worse at night * Pain may be accompanied by paresthesia in pelvic or veebral tumors Conservative treatment of pain can delay the diagnosis for weeks to months * Swelling- rapidly growing and painful, tense, elastic, hard with local raise of temperature. Not palpable if it is deep seated. Periods of remission can be present * Few cases present with pathological fractures * Weight loss, fatigue, intermittent pyrexia Signs * Palpable tender mass with prominent veins * Fever, erythema and swelling * Joints and neurological manifestation, joint effusion with limited mobility * Paralysis and root pain if spine involved Plain Radiography * Presents as extensive diaphyseal lesion * At midshaft of the long bone, the coex displays increased density, extending externally as periosteal new bone, forming multiple thin parallel layers giving &;onion peel appearence&; * Periosteal reactions may also have codmans triangle- lifting of periosteum from the bone. * Ewing sarcoma appears as ill defined, permeative, focally moth eaten, destructive intramedullary lesion accompanied by a periosteal reaction(onion skin) * Lesion may have both lytic and sclerotic regions * Extraosseous component is radiolucent with the same density of soft tissue. ref : maheswari 9th ed
Category: Orthopaedics
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