Faulty splicing can cause diseases: Splicing of hnRNA has to be performed with precision to produce functional mRNA. Faulty splicing may result in diseases. A good example is one type of beta-thalassemia in  humans. This is due to a mutation that results in a nucleotide change at an exon-intron junction. The result is a diminished or lack of synthesis of p-chain of hemoglobin, and consequently the disease p-thalassemia. Note:  scRNA - Small cytoplasmic RNA snoRNA - Small nucleolar RNA snRNA - Small nuclear RNA hnRNA - Heterogenous nuclear RNA Satyanarayana- Biochemistry, 3rd edition, pg-549