a 1 antitripsin deficiency is characterised by deposition of cytoplasmic inclusions which are:
Correct Answer: All of the above
Description: a1-Antitrypsin deficiency is characterized by the presence of round-to-oval cytoplasmic globular inclusions in hepatocytes, which in routine H&E stains are acidophilic and indistinctly demarcated from the surrounding cytoplasm. They are strongly periodic acid-Schiff (PAS)-positive and diastase-resistant Ref: Robbins 8th edition Chapter 18.
Category:
Pathology
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