In Hybrid RNA-DNA, DNA is 5CTTAAG3. The sequence of RNA will be:
Wait, in DNA replication, the DNA template is read in the 3' to 5' direction, and RNA is synthesized in the 5' to 3' direction. So when making RNA from DNA, the RNA is complementary to the DNA template strand. But in a hybrid RNA-DNA structure, like in transcription, the RNA is antiparallel to the DNA template. Let me think. The DNA given here is 5' CTTAAG 3', which would be the coding strand. The template strand would be the complementary strand, which is 3' GAATTC 5'. Then, RNA is transcribed from the template strand, replacing T with U. So the RNA sequence would be 5' CUUAAG 3', which is complementary to the DNA template. Wait, but the question says "Hybrid RNA-DNA". In a hybrid, the RNA would pair with the DNA template strand. So the RNA sequence should be complementary to the DNA template. Let me double-check. The DNA template is 3' GAATTC 5', so the RNA would be 5' CUUAAG 3'. Therefore, the RNA sequence is CUUAAG. But the options aren't listed here. Wait, the user didn't provide the options, but the correct answer is given as option C. So the user probably expects the answer to be the RNA sequence complementary to the DNA template. Let me confirm the base pairing: DNA T pairs with RNA A, DNA A with RNA U, DNA G with RNA C, and DNA C with RNA G. So the DNA template strand for 5' CTTAAG 3' (coding strand) is 3' GAATTC 5'. Therefore, RNA is 5' CUUAAG 3'. So the RNA sequence is CUUAAG. Therefore, the correct answer is option C if that's the option. The user's correct answer is listed as C. So the explanation should clarify that the RNA is complementary to the DNA template, which is the reverse complement of the given DNA sequence. The key here is understanding that the given DNA is the coding strand, and the RNA is synthesized from the template strand. Also, in RNA, thymine is replaced by uracil.
**Core Concept**
In DNA-RNA hybrids, RNA base-pairs with the DNA template strand via Watson-Crick complementarity. The RNA sequence is antiparallel to the DNA template and uses uracil (U) instead of thymine (T). The DNA coding strand (given here) is not directly transcribed; the template strand is its reverse complement.
**Why the Correct Answer is Right**
The given DNA sequence is the coding strand (5′-CTTAAG-3′). The RNA sequence is synthesized from the complementary DNA template strand. To determine this:
1. Find the DNA template strand by taking the reverse complement of the coding strand: 3′-GAATTC-5′.
2. Transcribe RNA by replacing T with U