46 year old female presented to OPD with complaints of breathlessness, purulent copious cough for 6 weeks. She lost 6 kg in 1.5 months. She was put on Clarithromycin and prednisolone for 2 weeks but there was no improvement in her condition . Chest Xray demonstrated persistent consolidation in the left lower lobe. What is the probable diagnosis of this patient?
Correct Answer: Adenocarcinoma in situ
Description: From the h/o purulent productive cough , loss of weight , and imaging study demonstrating consolidation in lung , adenocarcinoma in situ is a possibility and should be actively excluded by obtaining histology. Adenocarcinoma- seen in females & non smokers On CT scan , AIS is a nonsolid nodule On h/p, AIS shows lepidic growth with <=5 mm invasion 5-year disease-free survival = 100% , if complete tumor is resected
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