**Core Concept**
Spherophakia is a rare congenital or developmental anomaly of the lens characterized by a spherical shape instead of the normal biconvex shape. This condition leads to a decrease in lens elasticity and an increase in lens volume.

**Why the Correct Answer is Right**
The risk of cataract formation and subsequent glaucoma is significantly increased in patients with spherophakia. The spherical lens cannot accommodate properly, leading to increased intraocular pressure (IOP), which can cause glaucoma. Additionally, the lens may become dislocated due to its increased volume, leading to cataract formation.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because while cataract formation is a possible complication of spherophakia, it is not the most direct risk associated with this condition.
**Option B:** This option is incorrect because while glaucoma is a possible complication, it is not the most direct risk associated with spherophakia.
**Option C:** This option is incorrect because while dislocation of the lens is a possible complication, it is not the most direct risk associated with spherophakia.

**Clinical Pearl / High-Yield Fact**
It is essential for clinicians to recognize the association between spherophakia and glaucoma, as timely intervention can prevent vision loss. Patients with spherophakia should undergo regular ophthalmological evaluations to monitor IOP and lens status.

**Correct Answer:** D. Glaucoma