40-year-old immunocompromized patient presented with complaints of dysphagia. UGI scopy showed multiple ulcers in the distal esophagus. Biopsy from the esophagus showed the following. What is the diagnosis?

Correct Answer: Cytomegalovirus
Description: Ans. (b) Cytomegalovirus(Ref: Robbins 9th ed p 755)CMV causes shallower ulcerations and characteristic nuclear and cytoplasmic inclusions within capillary endothelium and stromal cells. Infected cells are strikingly enlarged, often to a diameter of 40 m, and show cellular and nuclear pleomorphism. Prominent intranuclear basophilic inclusions spanning half the nuclear diameter are usually set off from the nuclear membrane by a clear halo
Category: Pathology
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