11 hydroxylase deficiency leads to
Correct Answer: Hypeension
Description: Seen in Newborns and infants, Virilization and the presence of both hypeension and hypokalemia. 11 -deoxycoisol, 17a-hydroxyprogesterone, urinary 17- ketosteroids, and 17-hydroxycoicosteroids are increased. Blood levels and production rates of coisol are usually within normal limits. Physiologic replacement doses of glucocoicoid, such as hydrocoisone or dexamethasone, restores blood pressure to normal levels, corrects K+ depletion, Addition of estrogen-progestogen combined cyclic therapy may be necessary in the adult patient with 17a- hydroxylase deficiency. Reference: GHAI Essential pediatrics, 8th edition
Category:
Pediatrics
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