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714 Unknown

An anesthetized patient is mechanically ventilated at her normal tidal volume, but at twice her normal frequency. When mechanical ventilation is stopped, the patient fails to breathe spontaneously for 1 minute. This temporary cessation of breathing occurs because

AThe elevated arterial oxygen tension (Pao2) reduced peripheral chemoreceptor activity
BThe elevated (Pao2) reduced central chemoreceptor activity
CLow levels of nitrogen are known to inhibit ventilation
DThe lowered carbon dioxide tension (Pao2) reduced central chemoreceptor activity
Unknown
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719 Unknown

A 80-year-old male patient recently diagnosed with non-Hodgkin’s lymphoma was staed on treatment with R- CHOP chemotherapy regimen. After few days, the patient comes to the clinic with complaints of tingling in his hands and feet. Neurological examination shows symmetric “stocking and glove” type distal neuropathy. If the patient’s symptoms are believed to be due to chemotherapy regimen, the drug responsible for these symptoms causes cell cycle arrest during which of the following stages?

AG1-S transition
BS phase
CG2-M transition
DM phase
Unknown
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