Mcq Subject: Unknown
A 10-year-old male child with sho stature presented to the pediatric OPD with complaints of frequent headaches over the past 6 months along with slowly progressive loss of vision of the right eye. Lately the child has also staed having trouble in walking along with frequent mood changes and excessive thirst. MRI brain showed a tumour in the sellar region which was resected. HPE examination showed reticular epithelial cells that have appearances reminiscent of the enamel pulp of developing teeth along with calcifications and wet keratin nodules. The gene involved in causing the above condition is also involved in causing which other condition: –
A. Hepatocellular carcinoma
B. Melanoma
C. Neuroblastoma
D. CML
View DescriptionIn starvation activities of all of the following enzyme is increased except ?
A. Pyruvate carboxylase
B. Pyruvate kinase
C. PEP carboxykinase
D. Glucose 6 phosphatase
View DescriptionWhich of the following metabolic abnormality is seen in multiple myeloma –
A. Hyponatremia
B. Hypokalemia
C. Hypercalcemia
D. Hyperphosphatemia
View DescriptionWhen patient is on isotretinoin therapy, monitoring of which of the following is done
A. Liver function test
B. Lipid profile
C. Renal function tests
D. CBC
View DescriptionDigoxin toxicity may result from the concurrent administration of digoxin with all of the following drugs EXCEPT
A. Quinidine
B. Hydrochlorothiazide
C. Triamterene
D. Furosemide
View DescriptionPAS positive are all the following except –
A. Glycogen
B. Lipids
C. Fungal cell wall
D. Basement membrane of bacteria
View DescriptionAll are true regarding Crohn’s disease except:
A. Infertility
B. Risk of Ca
C. Medical treatment includes antibiotics, probiotics and TNF alpha blockers
D. ASCA-negative
View DescriptionWhich of the following predisposes to placenta previa?
A. Primigravida
B. Singleton pregnancy
C. Diabetesmellitus
D. Past cesarean pregnancy
View DescriptionA term born 6-month-old, lethargic blonde infant, presented with multiple episodes of vomiting, poor feeding, convulsions and severe psychomotor retardation. O/E: – Microcephaly with prominent maxillae and widely spaced teeth Blue iris Seborrheic or eczematoid rash Spasticity, hyperreflexia, and tremor Musty odour of urine MRI brain All of the following statements are true about the disease except: –
A. May be caused due to the deficiency of cofactor tetrahydrobiopterin BH4
B. Tandem mass spectrometry is useful in the diagnosis.
C. The complications can't be prevented by restricting the use of the involved amino acid in diet.
D. Pegvaliase can be given in adults suffering from this.
View DescriptionA female, Lalita, aged 26 yrs accidentally takes 100 tablets of paracetamol. What is the treatment of choice –
A. Lavage with charcoal
B. Dialysis
C. Alkaline diuresis
D. Acetylcysteine
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