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8648 Physiology

A 17-year-old soccer player suffered a fracture to the left tibia. After his lower leg has been in a cast for 8 weeks, he found that the left gastrocnemius muscle is significantly smaller in circumference than it was before the fracture. What is the most likely explanation?

ADecrease in the number of individual muscle fibers in the muscle.
BDecrease in blood flow to the muscle caused by constriction from the cast.
CTemporary reduction in actin and myosin protein synthesis (Correct Answer)
DProgressive denervation.