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4692 Physiology

A middle aged woman on oral contraceptives for many years, developed neurological symptoms such as depression, irritability, nervousness and mental confusion. Her hemoglobin level was 8g/cll. Biochemical investigations revealed that she was excreting highly elevated concentrations of xanthurenic acid in urine. She also showed high levels of triglycerides and cholesterol in serum. All of the above findings are most probably related to vitamin B6 deficiency caused by prolonged oral contraceptive use except :

AIncreased urinary xanthurenic acid excretion
BNeurological symptoms by decreased synthesis of biogenic amines
CDecreased hemoglobin level
DIncreased triglyceride and cholesterol level
Physiology
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4698 Physiology

A 38-year-old female presents to the physician with complaints of excessive thirst and urination for the past 4 weeks. Her appetite has been normal and she has not had diarrhea. Blood chemistry showed mildly elevated glucose and glucagon. Physical examination reveals tenderness in the left upper quadrant and an erythematous necrotizing skin eruption on her legs. Radiographic studies show a tumor in the pancreas. Which of the following cells is responsible for this lesion?

AAcinar cell
BAlpha cell
CBeta cell
DDelta cell
Physiology
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