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6662 Pharmacology

A healthy adult subject is given an intravenous injection of a test drug. Both blood pressure and total peripheral resistance rise promptly. This is followed immediately by a reduction of hea rate. In repeated experiments we find that the vasopressor response is not affected by pretreatment with prazosin. However, pretreatment with atropine prevents the cardiac chronotropic response. The test drug was most likely which of the following?

AAngiotensin II
BIsoproterenol
CNorepinephrine
DEpinephrine
Pharmacology
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6666 Pharmacology

True about propranalol is ?

AMetabolism of propranolol is not dependent on the hepatic blood flow
BUndergoes extensive first pass metabolism
CHydroxylated product of propranolol has alpha blocking propey
DPropranolol is lipophobic
Pharmacology
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6667 Pharmacology

Acetazolamide is

ACompetitive and reversible carbonic anhydrase inhibitor
BNon-competitive and reversible carbonic anhydrase inhibitor
CCompetitive and irreversible carbonic anhydrase inhibitor
DNon-competitive and irreversible carbonic anhydrase inhibitor
Pharmacology
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