Mcq Subject: Pharmacology

Mechanism of action of chlortetracycline:

A. Interfere with metabolism

B. Inhibition of protein synthesis

C. Inhibition of cell wall formation

D. Interfere with DNA function

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Which of the following is true for octreotide?

A. Stimulates growth hormone secretion

B. Used in secretory diarrhea

C. Orally active

D. Contraindicated in acromegaly

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A Pediatrician was called for attending a new born baby in the labour ward. The serum unconjugated bilirubin of this baby was 33 mg/dL. Which of the following drug taken by mother in late 3rd trimester may have lead to this problem?

A. Cotrimoxazole

B. Azithromycin

C. Ampicillin

D. Chloroquine

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Km value indicates:

A. Purity of Enzyme

B. Physiological role

C. The substrate concentration at half maximal velocity

D. Affinity

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Problems associated with nitrous oxide anaesthesia is

A. Behavioral problem

B. Sensitizes the heart to adrenaline

C. Prolonged difficult induction

D. Tachycardia and or arrhythmias

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Which of the following drugs is a P-glycoprotein inducer?

A. Azithromycin

B. Ketoconazole

C. Itraconazole

D. Rifampicin

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A female in labor ward was administered opioid analgesic. Which of the following drugs should be kept ready for emergency?

A. Lignocaine

B. Naloxone

C. Diphenhydramine

D. Fentanyl

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The process by which the amount of a drug in the body decreases after administration, but before entering the systemic circulation is called:

A. Excretion

B. First pass effect

C. First order elimination

D. Metabolism

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The organ most resistant to GA is

A. Spinal Cord

B. Medulla oblonagata

C. Medullary cortex

D. Cerebrum

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Mention the true/false statements about digoxin toxicity?

A. The earliest manifestation of digoxin toxicity are gastrointestinal symptoms

B. Non-specific vision changes may be noted in digoxin toxicity

C. Early toxicity may not correlate with serum levels and Neurological symptoms may occur without corresponding cardiovascular changes

D. All

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