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4304 Pharmacology

A 30 year old female with a 15 year history of asthma presents to the emergency room with left elbow pain. Physical examination reveals tenderness and swelling over the olecranon process. An x-ray of the left arm reveals a fracture. Her medications include oral prednisone and albuterol aerosol. By which of the following mechanisms might coicosteroids have contributed to her fracture?

ADecreased osteoblastic bone formation only
BDecreased osteoblastic bone formation and osteoclastic bone resorption
CIncreased osteoclastic bone resorption only
DIncreased osteoclastic bone resorption and decreased osteoblastic bone formation (Correct Answer)