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3580 Pharmacology

A 55-year-old woman is noted to be taking tamoxifen to help with breast cancer. She also complains of vaginal bleeding. Wof is the best explanation for vaginal bleeding

AIt is an estrogen antagonist in the breast and uterus, leading to loss of endometrial cells.
BIt has an antagonist effect on the breast but an agonist effect on the uterus.
CIt has estrogen agonist effect of the breast and uterus, thereby leading to endometrial hyperplasia.
DIt has no effect on the uterus, and the vaginal bleeding is caused by something else.
Pharmacology
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3581 Pharmacology

All are true about Digoxin except

ACauses bradycardia due to increased vagal tone causes bradycardia due to increase the vagal tone
BActs by inhibiting Na+K+ATPase in myocardial fibres
CIt is 95% plasma protein bound
DPrimaryly excreted unchanged by glomerular filtration
Pharmacology
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