Mcq Subject: Pharmacology

Which of the following is not an established antimicrobial drug synergism at clinical level?

A. Amphotericin B and flucytosine in cryptococcal meningitis

B. Carbenicillin and gentamicin in pseudomonal infections

C. Penicillin and tetracycline in bacterial meningitis

D. Trimethoprim and sulfamethoxazole in coliform infections

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Which one of the following drugs cause hypo magnesemia by increased excretion?

A. Frusemide therapy

B. Cisplatin

C. Digitalis

D. Aminoglycosides

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Which of the following is a mineralocoicoid antagonist ?

A. Spironolactone

B. Inamrinone

C. Nicorandil

D. Ketorolac

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Regarding propofol, which one of the following is false :

A. It is used as an intravenous induction agent

B. It causes severe vomiting

C. It is painful on injecting intravenously

D. It has no muscle relaxant property

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All act by inhibiting call wall synthesis except ?

A. Aminoglycoside

B. Penicillin

C. Cycloserine

D. Bacitracin

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In contrast to heparin, enoxaparin:

A. Can be used without monitoring the patient's aPTT

B. Is less likely to have a teratogenic effect

C. Is more likely to be given intravenously

D. Is more likely to cause thrombosis and thrombocytopenia

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Which of the following therapeutic index (T.I.) values represent the greatest safety profile for a drug?

A. 100

B. 1,000

C. 500

D. 2

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Ergot alkaloid commonly used to prevent postpartum hemorrhage is :

A. Methylergometrine

B. Ergotamine

C. Dihydroergotamine

D. Dihydroergotoxine

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In which type of poisonings is gastric lavage contraindicated?

A. Organophosphorus poisoning

B. Sedative drug poisoning

C. Corrosive acid poisoning

D. Barium carbonate poisoning

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Which of the following is the mechanism of action of methyl dopa?

A. Blockade of beta-adrenergic receptors

B. Agonism of alpha 2 receptors

C. Blockade of alpha 2 receptors

D. Agonism of beta 2 receptors.

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