Mcq Subject: Pharmacology

Propranolol is drug of choice for –

A. Ulcerated infantile hemangioma

B. Lymphangioma

C. Pyogenic granuloma

D. Capillary malformation

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Acetazolamide is given to a patient of angle closure glaucoma. It is a non- competitive inhibitor of carbonic anhydrase enzyme. Which of the following should be the effect of this drug?

A. Decrease in Vmax

B. Decrease in Km

C. Decrease in both Km and Vmax

D. No change in Vmax

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All are topical hemostatic agents except?

A. Bone wax & patty

B. HemCon bandage

C. Quikclot

D. Fixclot

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Dapsone is used for treatment of bacterial and fungal infections as well as for immunomodulatory actions. What is mechanism of dapsone for these indication?

A. Inhibition of cell wall synthesis

B. Inhibition of ergosterol in cell membranes

C. Inhibition of protein synthesis

D. Competition with PABA in folic acid synthesis

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Patient is a known case of epilepsy, taking levetiracetam 1 gm BD. He is now seizure free from 2 years but he developed agitation and anger issues interfering with day to day activities as a result of the drug intake. What should be the next best step?

A. Stop levetiracetam and sta on a different antiepileptic

B. Discontinue the drug as he is seizure free

C. Slowly taper the drug over next 6 months

D. Continue levetiracetam since a 5-year seizure free interval is needed

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One of the many mechanisms of adverse events is its increased binding to secondary targets, usually proteins. With respect to the primary target, the secondary target:

A. Should be present in the same tissue as the primary target

B. Should have similar binding sites

C. Should have absolutely identical secondary structure

D. Should have a similar primary structure

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Ganglionic transmission is mediated by:

A. Presynaptic alpha-receptors

B. Postsynaptic beta-receptors

C. Postsynaptic dopaminergic receptors

D. Postsynaptic nicotinic receptors

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Adverse effects of salbutamol are all except

A. Tremors

B. Tachycardia

C. Hypoglycemia

D. Hypokalemia

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The most common side effect of the oral administration of ampicillin is

A. Anaphylactic shock

B. Diarrhoea

C. Oral candidiasis

D. Renal failure

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A patient is administered 200 mg of a drug. 75 mg of the drug is eliminated from the body in 90 minutes. If the drug follows first order kinetics, how much drug will remain after 6 hours?

A. 12.5 mg

B. 25 mg

C. 30 mg

D. 50 mg

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