Mcq Subject: Pharmacology

Major mechanism of action of nitrates in acute attack of angina is:

A. Coronary vasodilation

B. Decrease in preload

C. Decrease in afterload

D. Decrease in hea rate

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Most commonly used route of administration of heparin for post-operative thromboprophylaxis is?

A. Subcutaneous

B. Intravenous

C. Inhalational

D. Intramuscular

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Like all opioids, tramadol acts as an analgesic drug by stimulating mu opioid receptors. Apa from this, the additional mechanism of action of tramadol is?

A. Serotonin and nor-adrenaline reuptake inhibition

B. Anticholinergic

C. Antihistaminic

D. Serotonin and dopamine reuptake inhibition

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A patient is of warfarin therapy. All of the following drugs increase the risk of bleeding with warfarin except?

A. Isoniazid

B. Amiodarone

C. Carbamazepine

D. Cimetidine

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A patient of septic shock was given intravenous norepinephrine. The response to this drug is best checked by:

A. Increase in hea rate

B. Decrease in hea rate

C. Increase in mean aerial pressure

D. Decreased renal perfusion and reduced urine output

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Lidocaine produces its antiarrhythmic effects by

A. Increasing A-V conduction

B. Decreasing cardiac excitability

C. Increasing cardiac conduction velocity

D. Increasing spontaneous pacemaker activity

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All are true of midazolam over diazepam except

A. 2 to 3 times more potent than diazepam

B. It has low water solubility and shows minimal risk for thrombophlebitis

C. Has more affinity for benzodiazepine receptors

D. Better anxiolysis and amnesia

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Not true about piperacilline is:

A. Active against pseudomonas aeruginosa

B. Inhibits Beta-lactamase

C. It is a ureido penicillin

D. Given parenterally

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Which of the following anticholinergic agent does not cross the blood brain barrier?

A. Glycopyrrolate

B. Atropine

C. Hyoscine butylbromide

D. Hyoscine hydrobromide

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Latest drug reccntly approved for Amyotrophic Lateral sclerosis is?

A. Piracetam

B. Ceftriaxone

C. Edaravone

D. Doxycycline

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