All Subjects Medicine Surgery Pathology Anatomy Pharmacology Social & Preventive Medicine Microbiology Gynaecology & Obstetrics Dental Physiology Biochemistry Pediatrics
Showing 14113 questions
Sort:
12640 Pharmacology

The positive inotropic effect of digitalis is due to inhibition of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to:

ADecreased activity of Na+/Ca++ exchanger causing decreased influx of sodium and decreased efflux of Ca++ in the sarcolemma
BDecreased efflux of Na+ leading to less negative resting membrane potential and opening of voltage gated Ca++ channels on the T tubules
CIncreased intracellular Na+ causing increased efflux of Na+ and increased influx of Ca++ through Na+/Ca++ exchanger in the sarcolemma
DIncreased intracellular Na+ decreasing the activity of Ca++ pump in the sarcoplasmic reticulum
Pharmacology
View Explanation →