Mcq Subject: Pharmacology

Which of the following drugs does not affect DNA synthesis?

A. Rifampicin

B. Linezolid

C. Nitrofurantoin

D. Metronidazole

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Drug binds to activate the receptor in same fashion, which directly or indirectly brings effect, is:

A. Inverse agonist

B. Antagonist

C. Agonist

D. Partial agonist

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If a bacteria were susceptible to both penicillin and Erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because

A. Penicillin is inactivated by erythromycin

B. Erythromycin exerts its effects extracellularly

C. Erythromycin enhances the β-lactamases activity

D. Penicillin is only effective against growing cells

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Which factor of the following contributes to short duration of anesthetic action of single dose thiopental

A. Rapid biotransformation

B. Rapid accumulation in body fat

C. High lipid solubility

D. Ability to enter and leave brain tissue every rapidly

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Pegloticase used in which of the following conditions?

A. Chronic Gout

B. Psoriatic ahritis

C. RA

D. Paralytic Ileus

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I.V. anesthesia is:

A. Propofol

B. Sevoflurane

C. Flumazanil

D. Naloxane

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Which anti-cholinergic drug doesn’t cross the blood brain barrier and placenta?

A. Glycopyrrolate bromide

B. Hyoscine bromide

C. Hyoscine butylbromide

D. Atropine

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Inter dose interval depends on?

A. Half life of drug

B. Dose of drug

C. Age of patient

D. Bioavailability of drug

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Mechanism of action of Oseltamivir (Tamiflu) as an antiviral agent is:

A. Inhibition of M2 receptor

B. Neuraminidase inhibition

C. Inhibition of RNA dependent DNA polymerase

D. Apoptosis of infected cells

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The drug which gives orange colour to the urine is:

A. Rifampicin

B. Ethambutol

C. INH

D. Streptomycin

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