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11240 Pharmacology

Loop diuretics such as furosemide act by :

ADecreasing tubular reabsorption of Na+ and increase GFR
BDecreasing FP secretion with resultant increase in Na+ and K+excretion
CInhibiting Na+ + K+ – 2Cl– co transporter in the medullary thick ascending limb (Correct Answer)
DInhibiting Na+ – K+exchange in the collecting duct