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11008 Pharmacology

Following a myocardial infarct, a patient is stabilized on warfarin, with the dose adjusted to give a prothrombin time of 22 seconds. Which one of the following statements regarding potential drug interactions in this patient is accurate?

ACholestyramine will increase prothrombin time.
BCimetidine is likely to decrease prothrombin time.
CAntibacterial sulfonamides may enhance the effects of warfarin. (Correct Answer)
DVitamin K would restore prothrombin time to normal within 30 minutes.