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10858 Pharmacology

Which of the following statements about the fluroquinolones is FALSE?

AGonococcal resistance to fluoroquinolones may involve changes in DNA gyrase
BModification of fluoroquinolones dosage is requyired in patients if creatinine clearance is less than 50 mL/min
CA fluroquinolone is the drug of choice for treatment of an unconmplicated urinary tract infection in a 7 year-old girl (Correct Answer)
DFluoroquinolones inhibit relaxation of positively supercoiled DNA