Mcq Subject: Pharmacology

Which of the following drug can decrease the size of prostate?

A. Tamsulosin

B. Sildenafil

C. Finasteride

D. Prazosin

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Ritonavir inhibits metabolism of all of the following drugs except:

A. Amiodarone

B. Phenytoin

C. Cisapride

D. Midazolam

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Which one of the following is a gender-specific side-effect of valproate?

A. Polycystic ovarian syndrome

B. Alopecia

C. Weight loss

D. Tremor

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Phase 1 clinical trial is done for:

A. Drug safety

B. Pharmacodynamics

C. Efficacy

D. Dosing

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Which one of the following antibiotics chelates with calcium ?

A. Penicillin

B. Tetracycline

C. Cephalosporins

D. Erythromycin

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Isosorbide 5 — mononitrate is preferred because

A. Less tolerance develops

B. Sublingual absorption is better

C. Longer duration of action

D. Direct coronary vasodilatory action is more

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Fixed drug eruptions are frequently seen with?

A. Penicillin

B. Sulfonamide

C. Cetirizine

D. Roxithromycin

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The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except:

A. Bradycardia

B. Decreased salivation

C. Decreased sweating

D. Mydriasis

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All of the following are true about Ifosfamide except:

A. It is nitrogen mustard

B. Metabolised by CYP3A4 to form active metabolite

C. Chloracetaldehyde is active form

D. Less neurotoxic than cyclophosphamide

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A patient was schedule for surgery. Before giving anaesthesia, he was administered glycopyrrolate. What is rationale of giving glycopyrrolate before anaesthesia?

A. To allay anxiety

B. To decrease secretions

C. As inducing agent

D. For muscle relaxation

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