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10565 Pharmacology

A 47-year-old woman presents with complaints of nervousness and increased sensitivity to hot weather. She is diagnosed with hypehyroidism and prescribed propylthiouracil. What is the principal mechanism by which this drug acts?

ADecreasing the efficacy of TSH binding to the thyroid TSH receptor
BDecreasing the rate of proteolysis of thyroglobulin
CIncreasing the amount of 3,3',5'-triiodothyronine (reverse T3; rT3)
DInhibiting deiodination of thyroxine (T4)
Pharmacology
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