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10364 Pharmacology

All of the following are features of inverse agonism except –

AIt is easier to observe inverse agonism if there is sufficient constitutive activity of receptor in the absence of agonist
BAn inverse agonist has a higher affinity for the active form of receptor as compared to the inactive form
CIf the equilibrium of receptor state lies in the direction of inactive confirmation in the absence of a ligand, it may be impossible to demonstrate inverse agonism
DFamoti di n e and losaan can be considered inverse agonists
Pharmacology
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