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9430 Pharmacology

Which of the following statements is not true of local anesthetics?

AThe local anesthetic is required in the unionized form for penetrating the neuronal membrane
BThe local anesthetic approaches its receptor only from the intraneuronal face of the Na+ channel
CThe local anesthetic binds to its receptor mainly when the Na+ channel is in the resting state
DThe local anesthetic combines with its receptor in the ionized cationic form
Pharmacology
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