Pathology MCQ Questions — Page 879

Question 1

Berger disease does not involve

AArtery

BVeins

CNerve

Answer

Lymphatics

Question 2

Sickle Cell anaemia all are true except

Answer

The shift from HbF to HbS occurs due to point mutation.

Answer

Microvascular occlusion is a severe complication of SCA

Answer

Deoxygenation of RBC can lead to extensive membrane damage

Answer

Adults but not children; with sickle cell disease are functionally asplenic, making them susceptible to infections caused by encapsulated bacteria, such as pneumococci.

Question 3

Most common gene responsible for hereditary hemochromatosis is?

AHJV gene

BHAMP gene

CTfR2 gene

DHFE gene

Question 4

The tumor suppressor gene P53 induces cell arrest at

DG0- phase

Answer

G2- M phase

Answer

S- G2 phase

Answer

G1-S phase

Question 5

Most demineralised zone in enamel caries

CDark zone

Answer

Translucent zone

Answer

Body of lession

Answer

Surface zone

Question 6

Mutation in PKHD1 gene causing autosomal recessive polycystic kidney disease (ARPKD) maps to which chromosome?

A16

B4

C6

D12

Question 7

A 19-year-old woman has noted swelling in the back of her mouth for 2 months. On dental examination, she has an area of swelling in the location of the left third molar. Dental radiographs show a radiolucent unilocular, well-circumscribed cyst surrounding the crown of the unerupted third mandibular molar. The lesion is excised, and on microscopic examination, the cyst is lined by stratified squamous epithelium and surrounded by a chronic inflammatory infiltrate. What is the most likely diagnosis?

DOdontoma

Answer

Ameloblastoma

Answer

Dentigerous cyst

Answer

Odontogenic keratocyst

Question 8

Pseudohypertrophy is seen in –

Answer

Facioscapulohumeral dystrophy

Answer

Emery Dreifuss muscular dystrophy

Answer

Myotonic dystrophy

Answer

Duchenne muscular dystrophy

Question 9

A 77-year-old man has had progressive dementia and gait ataxia for the past 9 years. He succumbs to bronchopneumonia. Autopsy shows that the thoracic aorta has a dilated root and arch, giving the intimal surface a “tree-bark” appearance. The microscopic examination of the aorta shows an obliterative endarteritis of the vasa vasorum. Which of the following laboratory findings is most likely to be recorded in this patient’s medical history?

Answer

Antibodies against Treponema pallidum

Answer

Double-stranded DNA titer positive at 1 :512

Answer

Ketonuria of 4+

Answer

P-ANCA positive at 1 :1024